March 14, 2025
With how widespread and impacting psoriasis is in the lives of people suffering from it, it isn’t surprising that much ongoing research has paved the way for new treatment options. Among them is biological therapy, which has gained a lot of popularity.
Biologic therapy for psoriasis specifically targets the molecules and pathways responsible for the inflammation and skin cell overproduction seen in psoriasis. So, unlike other autoimmune treatments, this one is much more precise and targeted.
In this Kayakalp Global guide, we will explain all the details about biologic therapy for psoriasis, its benefits, and whether or not it is suitable for your needs.
Given how foreign the concept of biologic therapy is, not many patients or their families are aware of what it does and how it is a breakthrough for treating psoriasis.
As previously mentioned, biologic therapy is a targeted autoimmune therapy in which the treatment directly targets the molecules and pathways that contribute to plaque formation on the skin due to the overproduction of skin cells.
These therapies are derived from living organisms and are designed to block certain proteins, such as tumor necrosis factor-alpha (TNF-alpha), interleukins (IL-12, IL-23, IL-17), or T-cells, which play key roles in the disease process.
Since the concept and introduction of biologic therapy are fairly new, it isn’t surprising that more and more patients are now getting acquainted with the idea of it. In fact, the treatment is more commonly recommended to patients suffering from moderate to severe cases of psoriasis who have not witnessed significant improvements in their symptoms after the ongoing treatments.
Now that you have an overview of what biologic therapy is, we must understand the different types of it and which are beneficial in treating psoriasis.
There are a few different types of biologic therapy for psoriasis, and the kind of biologics that would best work for the patient depends on the type of psoriasis and the severity of the symptoms.
Following are a few common types of biologics for psoriasis treatment:
These are the most common types of biologics used in treating psoriasis. These inhibitors block TNF-alpha, a protein that causes inflammation in the body. When the inflammation triggers are managed, psoriasis symptoms also eventually subside.
Who They Benefit: Patients with both plaque psoriasis and psoriatic arthritis.
Up next on the list are IL-12 and IL-23 inhibitors, which, as their names suggest, inhibit interleukins 12 and 23, proteins responsible for the overproduction of skin cells. These accumulated skin cells in psoriatic patients lead to plaque formation, which is what most patients complain about.
Who They Benefit: Patients with moderate to severe plaque psoriasis.
Another targeted biologic beneficial in treating psoriasis and its flaring symptoms is the IL-17 inhibitors. This compound directly targets interleukin-17, a cytokine responsible for psoriasis-related inflammation. It is one of the most effective biologics for patients suffering from stubborn plaque psoriasis.
Who They Benefit: Patients with stubborn plaque psoriasis.
Last but definitely not least on the list is T-cell inhibitors. As their name suggests, T-cell inhibitors prevent T-cells from activating and contributing to the inflammatory cycle. If you have received many traditional psoriasis treatments but they have not yielded the desired results, T-cell inhibitors are usually used as a last resort.
Who They Benefit: Patients unresponsive to traditional therapies.
Before we examine the benefits of biologic therapy for psoriasis and how it works, it is vital that we assess whether this treatment is best suited to your needs.
The question is, “Will your psoriasis benefit from undergoing biologic therapy?” If you are considering getting biologic therapy, the following are a few points of consideration:
If you have undergone all the traditional treatment options for psoriasis and none of them have yielded favorable results, you will only benefit from biologics.
Now, the next question to consider is, “Why Biological Therapy for psoriasis?” In short, what makes it so different?
Understanding the benefits of biologic therapy for psoriasis will let you understand the effectiveness of the treatment and why it is such a revolutionary breakthrough. The following are a few to consider:
These benefits of biologic therapy, along with its safety and effectiveness, depict why it is considered such an amazing option for patients wanting a long-term resolution for their psoriatic flare-ups.
Every potential medical treatment comes with a list of risks and side effects. These are a given, and you will be made aware of them during the initial consultation or before you undergo the treatment.
In the case of biologic therapy for psoriasis, the following are a few side effects to look out for:
These are rare side effects, and even if they happen, they are temporary, so you won’t necessarily have to worry about any long-term complications.
As a leading name in psoriasis treatment in India, Kayakalp Global is nothing short of a pioneer, having treated over 2 lac patients across the country.
If you are suffering from the symptoms, Kayakalp Global offers an integrated treatment approach that blends the power of Ayurveda with modern medicine. Following a detailed and thorough initial consultation, the patient is prescribed tests to determine the root cause of psoriasis, following which a personalized treatment plan is curated.
Our dermatologists and specialists are leaders in psoriasis management, with extensive experience in treatments that best align with the patient’s needs. Beyond biologics, we provide dietary, lifestyle, and mental health support to promote overall well-being.
Dealing with psoriasis can be extremely taxing on one’s mental and physical health. If you have been dealing with a similar situation and looking for effective treatment options, Kayakalp Global is the answer to all your woes.
Living with psoriasis can be challenging, but you don’t have to face it alone. Our specialists at Kayakalp Global are here to offer tailored, personalized, and compassionate care and guide you on your journey to healthier, happier skin.
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